In addition to taste, and other sensory aspects, a nicotine delivery similar to cigarettes is important in achieving acceptance by adult smokers.
Experts, including the U.S. Surgeon General and the U.K. Royal College of Physicians, agree that nicotine, while addictive, is not the primary cause of smoking-related diseases. Smoking-related diseases, such as lung cancer, cardiovascular disease, and emphysema, are caused primarily by inhaling harmful compounds largely formed when tobacco is burned, not by nicotine.
As the U.S. Food and Drug Administration (FDA) has stated, “inhalation of nicotine (i.e., nicotine without the production of combustion) is of less risk to a user than the inhalation of nicotine delivered by smoke from combusted tobacco products.”